Diet palatability and amphetamine-induced anorexia

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Defense of body weight depends on dietary composition and palatability in rats with diet-induced obesity.

Sprague-Dawley rats selectively bred for diet-induced obesity (DIO) or diet resistance (DR) were characterized on diets of differing energy content and palatability. Over 10 wk, DR rats on a high-energy (HE) diet (31% fat) gained weight similarly to DR rats fed chow (4.5% fat), but they became obese on a palatable liquid diet (Ensure). DIO rats gained 22% more weight on an HE diet and 50% more ...

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Diet Therapy of Anorexia Nervosa

AN is often associated with denial of illness and resistance to treatment. Consequently it is difficult to engage individuals with AN in treatment, including nutritional restoration, and weight normalization. The continuous restrictive eating and malnutrition result in pervasive disturbances of most organ systems including cardiovascular and gastrointestinal complications, endocrine disorders (...

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Amphetamine induced dopamine release increases anxiety in individuals recovered from anorexia nervosa.

OBJECTIVE Genetic, pharmacologic, and physiological data suggest that individuals with anorexia nervosa (AN) have altered striatal dopamine (DA) function. METHOD We used an amphetamine challenge and positron emission tomography [(11) C]raclopride paradigm to explore DA striatal transmission in 10 recovered (REC) AN compared with 9 control women (CW). RESULTS REC AN and CW were similar for b...

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Diet Therapy of Anorexia Nervosa

AN is often associated with denial of illness and resistance to treatment. Consequently it is difficult to engage individuals with AN in treatment, including nutritional restoration, and weight normalization. The continuous restrictive eating and malnutrition result in pervasive disturbances of most organ systems including cardiovascular and gastrointestinal complications, endocrine disorders (...

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INFLUENCES OF DIFFERENT ADRENOCEPTOR AGONISTS AND ANTAGONISTS ON AMPHETAMINE- INDUCED CLIMBING IN MICE

Administration of apomorphine and amphetamine induces climbing behavior in mice due to stimulation of brain dopamine receptors. In the present study, the effects of adrenoceptor agonists and antagonists on amphetamine-induced climbing have been investigated. Intraperitoneal (i.p.) injection of different doses of amphetamine (2,4 and 8 mglkg) induced climbing in mice (p<O.OOO 1). The u2- ad...

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ژورنال

عنوان ژورنال: Physiological Psychology

سال: 1982

ISSN: 0090-5046

DOI: 10.3758/bf03327015